GHRP-6 | 5mg & 10mg

Product OverviewGHRP-6 (Growth Hormone Releasing Hexapeptide) is a synthetic hexapeptide and a prominent member of the growth hormone secretagogue (GHS) class. It acts as an agonist of the ghrelin receptor, specifically GHS-R1a. Laboratory studies utilise this compound to investigate the somatotropic axis and its modulation in various in vitro and animal models.This compound undergoes rigorous analytical testing to ensure structural integrity for research applications. Each batch is synthesised and purified to exceed standard laboratory requirements, providing researchers with reliable baseline data for cellular assays and receptor-binding investigations.Technical SpecificationsChemical Name: Growth Hormone Releasing HexapeptideCAS Number: 87616-84-0Sequence: His-D-Trp-Ala-Trp-D-Phe-Lys-NH2Molecular Formula: C46H56N12O6Molecular Weight: 873.01 g/molTarget: Ghrelin receptor (GHS-R1a)Mechanism: GHS-R1a agonismHalf-Life: ~20-30 minutesFormat: Lyophilised SolidAppearance: White crystalline powderGrade: Laboratory / Analytical GradePurity: >99% HPLC VerifiedVariant Breakdown5mg Lyophilised Vial10mg Lyophilised VialClosure: Rubber stopper with flip-off aluminium seal.Research Mechanism (Mechanism of Action)Receptor Binding: GHRP-6 exhibits high affinity for the GHS-R1a receptor, which is densely expressed in the anterior pituitary and hypothalamic tissue of animal subjects.Signal Transduction: Binding initiates a phospholipase C-dependent intracellular signalling cascade. This process elevates inositol triphosphate (IP3) and diacylglycerol (DAG) levels within target cells.Cellular Response: The biochemical cascade stimulates the release of intracellular calcium ions, prompting the exocytosis of secretory vesicles.Safety, Handling & ReconstitutionAccurate reconstitution is required to maintain peptide stability. Utilise Bacteriostatic Reconstitution Solution (0.9% Benzyl Alcohol) for optimal dissolution. Store the lyophilised solid at -20°C. Once reconstituted, the solution must be stored between 2°C and 8°C. This material is strictly for Laboratory Research Purposes Only.Scientific References (External Links)Journal of Endocrinology: “Growth hormone-releasing peptide-6 (GHRP-6) action in the hypothalamus” View StudyNeuroendocrinology: “Mechanisms of action of GHRP-6 on somatotrope cells” View StudyPeptides: “The effects of GHRP-6 on the gastrointestinal tract in animal models” View StudyMolecular and Cellular Endocrinology: “Intracellular signalling pathways of GHRP-6 in pituitary cell cultures” View Study